Lymphocytic Interstitial Pneumonia Presenting With Haemoptysis and a Solitary Spiculated Pulmonary Nodule: A Case Report

Lymphocytic interstitial pneumonia (LIP) is a rare disorder that typically presents with cystic changes on computed tomography. We report a distinctive case of a 53-year-old man with LIP whose sole presenting symptom was haemoptysis. Imaging revealed a solitary spiculated pulmonary nodule, highly suspicious for malignancy. Diagnosis was confirmed by surgical resection and histopathology, which demonstrated characteristic diffuse lymphoplasmacytic infiltration. This case underscores that LIP can masquerade radiologically as lung cancer and must be considered in the differential diagnosis of solitary pulmonary nodules, emphasising the indispensability of pathological confirmation.

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Publication Details

Journal
Respirology Case Reports
Published
2025-11-29
DOI
https://doi.org/10.1002/rcr2.70416
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Lymphocytic Interstitial Pneumonia Presenting With Haemoptysis and a Solitary Spiculated Pulmonary Nodule: A Case Report

Huiming Yin, Lei Jianming, Cheng Jiang, Fei Han et al.
Respirology Case Reports
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Lymphocytic Interstitial Pneumonia Presenting With Haemoptysis and a Solitary Spiculated Pulmonary Nodule: A Case Report

Huiming Yin, Lei Jianming, Cheng Jiang, Fei Han, Jie Lin, Xiaomei Zhong
article en

Abstract

Lymphocytic interstitial pneumonia (LIP) is a rare disorder that typically presents with cystic changes on computed tomography. We report a distinctive case of a 53-year-old man with LIP whose sole presenting symptom was haemoptysis. Imaging revealed a solitary spiculated pulmonary nodule, highly suspicious for malignancy. Diagnosis was confirmed by surgical resection and histopathology, which demonstrated characteristic diffuse lymphoplasmacytic infiltration. This case underscores that LIP can masquerade radiologically as lung cancer and must be considered in the differential diagnosis of solitary pulmonary nodules, emphasising the indispensability of pathological confirmation.

Respirology Case ReportsVol. 13(12)
Huaian First People’s Hospital (CN), First Affiliated Hospital of University of South China (CN), University of South China (CN)
Openalex Percentile: Top 44%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Lymphocytic Interstitial Pneumonia Presenting With Haemoptysis and a Solitary Spiculated Pulmonary Nodule: A Case Report — Huiming Yin, Lei Jianming, et al. · Respirology Case Reports (2025) | TGRS Research Map | TGRS