Adaptation of Axillary Reverse Mapping Using Methylene Blue Dye for the Prevention of Post-Mastectomy Lymphedema: A Low-Cost Alternative to Radiotracers

Methylene blue-based ARM is feasible and associated with lower lymphedema incidence and reduced arm swelling in this cohort. Findings should be interpreted cautiously due to the observational design, small sample size, short follow-up, and limited safety monitoring. These results indicate an association rather than established causal effectiveness and suggest that methylene blue may be a practical alternative to radiotracers in resource-limited settings.