Text-to-music generation models capture musical semantic representations in the human brain

Aligning brain activity with machine-learning models offers a way to understand how the brain represents the world, and such models relate to the brain. In this paper, we explore the functional correspondence between music-specific information and brain activity. Using fMRI, we reconstruct music either via retrieval or by conditioning the MusicLM generator on brain data. The generated music resembles the musical stimuli that human subjects experienced with respect to semantic properties such as genre, instrumentation, and mood. Using an encoding modeling analysis, we also demonstrate that semantic information derived from music, as well as information derived from purely textual descriptions of music stimuli, are represented in a largely overlapped region around the auditory cortex. Furthermore, we show that features from MusicLM predicted brain activity within the primary auditory cortex more accurately than the non-music models that do not specifically focus on music.

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Publication Details

Journal
Nature Communications
Published
2025-11-29
DOI
https://doi.org/10.1038/s41467-025-66731-7
Primary Topic
Neuroscience and Music Perception
Type
article
Field-Weighted Citation Impact
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article

Text-to-music generation models capture musical semantic representations in the human brain

Tomoya Nakai, Shinji Nishimoto, Timo I. Denk, Christian Frank et al.
Nature Communications
Neuroscience and Music Perception
article

Text-to-music generation models capture musical semantic representations in the human brain

Tomoya Nakai, Shinji Nishimoto, Timo I. Denk, Christian Frank, Yu Takagi, Andrea Agostinelli, Takuya Matsuyama
article en

Abstract

Aligning brain activity with machine-learning models offers a way to understand how the brain represents the world, and such models relate to the brain. In this paper, we explore the functional correspondence between music-specific information and brain activity. Using fMRI, we reconstruct music either via retrieval or by conditioning the MusicLM generator on brain data. The generated music resembles the musical stimuli that human subjects experienced with respect to semantic properties such as genre, instrumentation, and mood. Using an encoding modeling analysis, we also demonstrate that semantic information derived from music, as well as information derived from purely textual descriptions of music stimuli, are represented in a largely overlapped region around the auditory cortex. Furthermore, we show that features from MusicLM predicted brain activity within the primary auditory cortex more accurately than the non-music models that do not specifically focus on music.

Nature CommunicationsVol. 17(1)
Google (United States) (US), Nagoya Institute of Technology (JP), Sakarya Eğitim ve Araştırma Hastanesi (TR), National Institute of Information and Communications Technology (JP), The University of Osaka (JP)
Openalex Percentile: Top 63%
Neuroscience and Music Perception
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