Cytodiagnosis of Multicentric Giant Cell Tumour of Tendon Sheath: A Rare Case Report

Giant Cell Tumour of Tendon Sheath (GCTTS) is a benign soft-tissue tumour that commonly arises from the tendon sheath complex and periarticular soft tissue of small joints. These tumours are usually localised and solitary, with multiple occurrences being rare. A multicentric origin is considered unusual and very few cases have been reported to date. Hereby, the authors present a case report of a 40-year-old female with a history of multiple swellings over the bilateral tendo-Achillis region, knees, left great toe and dorsum of the right middle finger since, 10 years ago. Biochemical parameters were normal and radiological investigations did not reveal any bony abnormalities. Fine needle aspiration from all sites revealed features consistent with GCTTS. Histopathology also showed findings typical of GCTTS. The present case highlights the unusual multicentric presentation of GCTTS.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2025-11-29
DOI
https://doi.org/10.7860/jcdr/2026/80360.22300
Primary Topic
Musculoskeletal synovial abnormalities and treatments
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article
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article

Cytodiagnosis of Multicentric Giant Cell Tumour of Tendon Sheath: A Rare Case Report

Y K Sharma, Aparajita Mishra, P Mishra, Sarmistha Subhadarshini et al.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Musculoskeletal synovial abnormalities and treatments
article

Cytodiagnosis of Multicentric Giant Cell Tumour of Tendon Sheath: A Rare Case Report

Y K Sharma, Aparajita Mishra, P Mishra, Sarmistha Subhadarshini, Jagdish Kumar Behera
article en

Abstract

Giant Cell Tumour of Tendon Sheath (GCTTS) is a benign soft-tissue tumour that commonly arises from the tendon sheath complex and periarticular soft tissue of small joints. These tumours are usually localised and solitary, with multiple occurrences being rare. A multicentric origin is considered unusual and very few cases have been reported to date. Hereby, the authors present a case report of a 40-year-old female with a history of multiple swellings over the bilateral tendo-Achillis region, knees, left great toe and dorsum of the right middle finger since, 10 years ago. Biochemical parameters were normal and radiological investigations did not reveal any bony abnormalities. Fine needle aspiration from all sites revealed features consistent with GCTTS. Histopathology also showed findings typical of GCTTS. The present case highlights the unusual multicentric presentation of GCTTS.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Openalex Percentile: Top 47%
Musculoskeletal synovial abnormalities and treatments
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