Adult-onset generalized seizures in undiagnosed cerebral hemiatrophy: A case of Dyke-Davidoff-Masson syndrome

Dyke-Davidoff-Masson syndrome (DDMS), is a rare neurological disorder commonly diagnosed in childhood which is characterized by cerebral hemiatrophy, leading to seizures, hemiparesis, and varying degrees of cognitive deficits. This case report describes the case of a 45-year-old lady who presented with loss of consciousness and generalized tonic-clonic seizures. Despite a history of gait abnormality and right upper limb motor deficit since childhood, the diagnosis of DDMS was not established until this acute event in adulthood, and the patient exhibited no apparent gross cognitive deficits. This delayed presentation, following years of subtle neurological signs, expands the recognized clinical spectrum of this rare condition.