Identification of NS5B resistance-associated mutations in hepatitis C virus circulating in treatment-naïve Cameroonian patients

Our investigation revealed that HCV patients who had not previously received DAA therapy exhibited a variety of NS5B gene alterations. Consequently, future treatment failure may be more likely due to these alterations.

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Publication Details

Journal
IJID Regions
Published
2025-11-29
DOI
https://doi.org/10.1016/j.ijregi.2025.100816
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of NS5B resistance-associated mutations in hepatitis C virus circulating in treatment-naïve Cameroonian patients

Simon Frédéric Lissock, Chavely Gwladys Monamele, Richard Njouom, Paul Alain Tagnouokam‐Ngoupo et al.
IJID Regions
Hepatitis C virus research
article

Identification of NS5B resistance-associated mutations in hepatitis C virus circulating in treatment-naïve Cameroonian patients

Simon Frédéric Lissock, Chavely Gwladys Monamele, Richard Njouom, Paul Alain Tagnouokam‐Ngoupo, Jean Paul Assam Assam, Abdou Fatawou Modiyinji, Pretty Rosereine Mbouyap, Aristide Mounchili-Njifon, Moise Henri Moumbeket-Yifomnjou, Gisèle Liliane Machuetum, Philipe Herman Njitoyap Mfombouot, Pascal Ibrahim Toueyem
article en

Abstract

Our investigation revealed that HCV patients who had not previously received DAA therapy exhibited a variety of NS5B gene alterations. Consequently, future treatment failure may be more likely due to these alterations.

IJID RegionsVol. 18
Université de Yaoundé I (CM), Centre Pasteur du Cameroun (CM)
Openalex Percentile: Top 51%
Hepatitis C virus research
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