Association between hysterectomy, oophorectomy, and risk of breast cancer: a meta-analysis
This meta-analysis suggests that both hysterectomy and oophorectomy are significantly associated with a reduction in breast cancer risk. The effectiveness of bilateral oophorectomy appears to be modulated by hormone therapy and menopausal status. Further research is needed to clarify these associations and to explore the underlying biological mechanisms.
Authors
- Huili Xu
- Yu Liu (ORCID: https://orcid.org/0000-0002-6681-2293)
- Bing Wang (ORCID: https://orcid.org/0000-0003-4945-7725)
- Yang Cao (ORCID: https://orcid.org/0000-0003-3230-5346)
- Meng Wang (ORCID: https://orcid.org/0000-0001-7293-0408)
- Tengteng Kang
Institutions
- Hubei University of Medicine (CN)
- Universiti Putra Malaysia (MY)
- Jilin University (CN)
- Zhoukou Normal University (CN)
- First Hospital of Jilin University (CN)
- Changchun University of Chinese Medicine (CN)
- Chinese People's Armed Police Force
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1007/s00404-025-08179-0
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00