Joint range‐modulator and spot optimization for Bragg‐peak proton FLASH radiotherapy

A new optimization method JRSO is proposed for conformal pFLASH radiotherapy. It outperforms the conventional approach and may extend the applicability of PSRM to more complex clinical scenarios, particularly those involving misalignments between beam spots and pins. Numerical results demonstrate the robustness and efficiency of the new method.

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Publication Details

Journal
Medical Physics
Published
2025-11-28
DOI
https://doi.org/10.1002/mp.70171
Citations
1
Primary Topic
Radiation Therapy and Dosimetry
Type
article
Field-Weighted Citation Impact
1.52
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article

Joint range‐modulator and spot optimization for Bragg‐peak proton FLASH radiotherapy

Wangyao Li, Jiangchao Han, Aoxiang Wang, Hao Gao et al.
1 citations
Medical Physics
Radiation Therapy and Dosimetry
1.52
article

Joint range‐modulator and spot optimization for Bragg‐peak proton FLASH radiotherapy

Wangyao Li, Jiangchao Han, Aoxiang Wang, Hao Gao, Yuting Lin, Ya‐Nan Zhu
article en
1 citations

Abstract

A new optimization method JRSO is proposed for conformal pFLASH radiotherapy. It outperforms the conventional approach and may extend the applicability of PSRM to more complex clinical scenarios, particularly those involving misalignments between beam spots and pins. Numerical results demonstrate the robustness and efficiency of the new method.

Medical PhysicsVol. 52(12)
Harbin Institute of Technology (CN), University of Kansas Medical Center (US), Huazhong University of Science and Technology (CN), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 12%
Radiation Therapy and Dosimetry
1.52
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