Dermal Alpha‐Synuclein Aggregation in Seed Amplification Assays for Parkinson's Disease Subtype Differentiation
Our data suggest that widespread α-syn aggregation in advanced PD limits the use of SAA in skin biopsies for subtype differentiation.
Authors
- Annette Janzen (ORCID: https://orcid.org/0000-0001-8907-5831)
- Jens Volkmann (ORCID: https://orcid.org/0000-0002-9570-593X)
- Anastasia Kuzkina (ORCID: https://orcid.org/0000-0001-5443-8540)
- Wolfgang H. Oertel (ORCID: https://orcid.org/0000-0002-7582-8166)
- Kathrin Doppler (ORCID: https://orcid.org/0000-0003-2883-0009)
- Michael Sommerauer (ORCID: https://orcid.org/0000-0001-5723-9766)
- Magdalena Vieregge
Institutions
- Brigham and Women's Hospital (US)
- University of Bonn (DE)
- Philipps University of Marburg (DE)
- Forschungszentrum Jülich (DE)
- German Center for Neurodegenerative Diseases (DE)
- Helmholtz Zentrum München (DE)
- Universitätsklinikum Würzburg (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1111/ene.70453
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung