Associations between modifiable factors and early-onset breast cancer mortality among patients

Being overweight or obese before an early-onset breast cancer diagnosis is associated with increased breast cancer-specific mortality. Although the potential underlying biological mechanisms remain inconclusive, it likely involves complex hormonal alterations related to changes in body adiposity. As voluntary weight loss is generally not advised during cancer treatment, maintaining a healthy weight throughout adulthood is strongly encouraged to reduce numerous health risks, including excess mortality in young breast cancer patients.

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Publication Details

Journal
BMC Cancer
Published
2025-11-29
DOI
https://doi.org/10.1186/s12885-025-15226-1
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
0.00
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Associations between modifiable factors and early-onset breast cancer mortality among patients

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article en

Abstract

Being overweight or obese before an early-onset breast cancer diagnosis is associated with increased breast cancer-specific mortality. Although the potential underlying biological mechanisms remain inconclusive, it likely involves complex hormonal alterations related to changes in body adiposity. As voluntary weight loss is generally not advised during cancer treatment, maintaining a healthy weight throughout adulthood is strongly encouraged to reduce numerous health risks, including excess mortality in young breast cancer patients.

BMC CancerVol. 26(1)
Agency for Science, Technology and Research (SG), The University of Sydney (AU), University of Helsinki (FI), National University of Singapore (SG), Tampere University (FI), Helsinki University Hospital (FI), Finnish Institute for Health and Welfare (FI), Finnish Cancer Registry (FI), Singapore Institute for Clinical Sciences (SG), Folkhälsans Forskningscentrum (FI)
Openalex Percentile: Top 48%
Cancer Risks and Factors
DOIOpen Access PDFOpenAlex
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