Giant Meckel’s Diverticulum Presenting as Chronic Iron-Deficiency Anemia in a Young Adult: A Rare Clinical Entity

Meckel’s diverticulum is the most prevalent congenital anomaly of the gastrointestinal tract, yet it often remains asymptomatic and undiagnosed. Giant Meckel’s diverticulum, defined as a diverticulum exceeding 5 cm in length, is extremely rare and can present with complications, including bleeding, obstruction, and inflammation. We report a case of a 21-year-old female who presented with chronic iron deficiency anemia, generalized weakness, and intermittent passage of blackish stools for several months. Despite upper and lower gastrointestinal endoscopies showing no significant pathology, a contrast-enhanced MDCT scan of the abdomen revealed a 10 cm long blind-ending tubular structure arising from the distal ileum, consistent with a giant Meckel’s diverticulum. The diverticulum contained food particles and an air-fluid level, suggesting chronic stasis. Multiple enlarged mesenteric lymph nodes were also noted. The patient was managed conservatively and advised of elective surgical resection. This case emphasizes the need to consider Meckel’s diverticulum in the differential diagnosis of unexplained chronic anemia in young adults, especially when standard endoscopic evaluations are inconclusive. Cross-sectional imaging plays a crucial role in establishing the diagnosis.

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Journal
International journal of Nutrition Pharmacology Neurological Diseases
Published
2025-10-01
DOI
https://doi.org/10.4103/ijnpnd.ijnpnd_58_25
Primary Topic
Gastrointestinal disorders and treatments
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article
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article

Giant Meckel’s Diverticulum Presenting as Chronic Iron-Deficiency Anemia in a Young Adult: A Rare Clinical Entity

Nikhil Reddy, Sourya Acharya, Faizan Khan, Avinash Parepalli et al.
International journal of Nutrition Pharmacology Neurological Diseases
Gastrointestinal disorders and treatments
article

Giant Meckel’s Diverticulum Presenting as Chronic Iron-Deficiency Anemia in a Young Adult: A Rare Clinical Entity

Nikhil Reddy, Sourya Acharya, Faizan Khan, Avinash Parepalli, Utkarsh Pradeep, Sunil Kumar
article en

Abstract

Meckel’s diverticulum is the most prevalent congenital anomaly of the gastrointestinal tract, yet it often remains asymptomatic and undiagnosed. Giant Meckel’s diverticulum, defined as a diverticulum exceeding 5 cm in length, is extremely rare and can present with complications, including bleeding, obstruction, and inflammation. We report a case of a 21-year-old female who presented with chronic iron deficiency anemia, generalized weakness, and intermittent passage of blackish stools for several months. Despite upper and lower gastrointestinal endoscopies showing no significant pathology, a contrast-enhanced MDCT scan of the abdomen revealed a 10 cm long blind-ending tubular structure arising from the distal ileum, consistent with a giant Meckel’s diverticulum. The diverticulum contained food particles and an air-fluid level, suggesting chronic stasis. Multiple enlarged mesenteric lymph nodes were also noted. The patient was managed conservatively and advised of elective surgical resection. This case emphasizes the need to consider Meckel’s diverticulum in the differential diagnosis of unexplained chronic anemia in young adults, especially when standard endoscopic evaluations are inconclusive. Cross-sectional imaging plays a crucial role in establishing the diagnosis.

International journal of Nutrition Pharmacology Neurological DiseasesVol. 15(4)
Jawaharlal Nehru Medical College (IN), Datta Meghe Institute of Higher Education and Research (IN)
Openalex Percentile: Top 44%
Gastrointestinal disorders and treatments
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Giant Meckel’s Diverticulum Presenting as Chronic Iron-Deficiency Anemia in a Young Adult: A Rare Clinical Entity — Nikhil Reddy, Sourya Acharya, et al. · International journal of Nutrition Pharmacology Neurological Diseases (2025) | TGRS Research Map | TGRS