SEOM-GEICAM-SOLTI clinical guidelines for early-stage breast cancer (UPDATE 2025)
Breast cancer is the leading cause of cancer in women in Spain and its annual incidence is rapidly increasing. As a result of the screening programs in place, nearly 90% of breast cancer cases are detected in early and potentially curable stages. In recent years, locoregional and systemic therapies have increasingly been directed by new diagnostic tools that have improved the balance between toxicity and clinical benefit. New therapeutic strategies, such as immunotherapy, targeted drugs, and antibody-drug conjugates, have also improved outcomes in some patient subgroups. This clinical practice guideline for early-stage breast cancer (updated in 2025) is based on a systematic review of relevant studies and on the consensus of experts from the Spanish Breast Cancer Research Group (GEICAM), Spanish Collaborative Group for the Study, Treatment and Other Experimental Strategies in Solid Tumors (SOLTI), and Spanish Society of Medical Oncology (SEOM).
Authors
- María Vidal (ORCID: https://orcid.org/0000-0003-1992-5727)
- Francisco Ayala (ORCID: https://orcid.org/0000-0001-6311-920X)
- Joaquín Gavilá Gregori (ORCID: https://orcid.org/0000-0002-6768-3833)
- Lucía González Cortijo (ORCID: https://orcid.org/0000-0003-2082-670X)
- Cristina Morales Estévez (ORCID: https://orcid.org/0000-0002-6541-8235)
- Silvia Antolín (ORCID: https://orcid.org/0000-0002-0110-3349)
- Agostina Stradella (ORCID: https://orcid.org/0000-0002-2307-8869)
- Fernando Henao (ORCID: https://orcid.org/0000-0003-3819-9572)
- Eva Ciruelos (ORCID: https://orcid.org/0000-0002-2796-1042)
- María Teresa Martínez (ORCID: https://orcid.org/0000-0003-1312-3555)
Institutions
- Hospital General Universitario Gregorio Marañón (ES)
- Research Institute Hospital 12 de Octubre (ES)
- Hospital Universitario Virgen Macarena (ES)
- Fundación Instituto Valenciano de Oncología (ES)
- Institut Català d'Oncologia (ES)
- Hospital Universitario Quirónsalud Madrid (ES)
- Hospital Clínic de Barcelona (ES)
- HM Hospitales (ES)
- Hospital Universitario Reina Sofía (ES)
- Complexo Hospitalario Universitario A Coruña (ES)
- INCLIVA Health Research Institute (ES)
Publication Details
- Journal
- Clinical & Translational Oncology
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1007/s12094-025-04139-x
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sociedad Española de Oncología Médica