Ectopic thymoma arising in the pleura: Diagnostic challenges and clinical implications: A case report

Thymoma is a rare tumor originating from the thymic epithelium, typically located in the anterior mediastinum. Ectopic thymomas are extremely uncommon and may occur in the neck, middle or posterior mediastinum, lung, or pleura. We report the case of a 62-year-old woman presenting with cough, weight loss, and asthenia. Chest computed tomography (CT) revealed a right pleural mass. Complete surgical resection was performed, and the postoperative diagnosis confirmed a WHO Type AB thymoma, classified as Masaoka-Koga stage IIa. Following surgery, she underwent adjuvant radiotherapy, and no recurrence was observed during follow-up.

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Publication Details

Journal
Radiology Case Reports
Published
2025-11-27
DOI
https://doi.org/10.1016/j.radcr.2025.11.012
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Ectopic thymoma arising in the pleura: Diagnostic challenges and clinical implications: A case report

Letizia Laera, Mario Di Diego, Fabio Laterza, Michele Dezio et al.
Radiology Case Reports
Myasthenia Gravis and Thymoma
article

Ectopic thymoma arising in the pleura: Diagnostic challenges and clinical implications: A case report

Letizia Laera, Mario Di Diego, Fabio Laterza, Michele Dezio, Roberto Calbi, Stefania Marini, Angela Calabrese, Roberta Dattoli, Monica Cozzolino, A Pisani, Diletta De Lucia
article en

Abstract

Thymoma is a rare tumor originating from the thymic epithelium, typically located in the anterior mediastinum. Ectopic thymomas are extremely uncommon and may occur in the neck, middle or posterior mediastinum, lung, or pleura. We report the case of a 62-year-old woman presenting with cough, weight loss, and asthenia. Chest computed tomography (CT) revealed a right pleural mass. Complete surgical resection was performed, and the postoperative diagnosis confirmed a WHO Type AB thymoma, classified as Masaoka-Koga stage IIa. Following surgery, she underwent adjuvant radiotherapy, and no recurrence was observed during follow-up.

Radiology Case ReportsVol. 21(2)
Agostino Gemelli University Polyclinic (IT), Istituto Tumori Bari (IT), Ospedale Generale Regionale Francesco Miulli (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Bari Aldo Moro (IT)
Openalex Percentile: Top 49%
Myasthenia Gravis and Thymoma
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