Keratoacanthomas Over Pre-existing Discoid Lupus Erythematosus: A Rare Case Report

Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus erythematosus, resulting in scarring and atrophy. Keratoacanthoma (KA) is a borderline cutaneous malignancy that is known to have a rapid evolution but spontaneous regression or good prognosis. The development of malignancies like squamous cell carcinoma over DLE plaque is known. The use of antimalarials for treatment with a better understanding of the disease has led to a decrease in the incidence of such a phenomenon. Thus, in this era, the occurrence of KA over DLE is extremely rare. Herein, we report a rare case of KA occurring over a DLE plaque in a 50-year-old patient. The patient was diagnosed based on clinico-histopathological correlation, and then started on acitretin, and referred to surgical oncology for excision of the tumour.