Radiographic assessment of segmental correction and subsidence following posterior lumbar fusion with expandable interbody cages: a 12-month retrospective cohort study

Expandable interbody cages have gained popularity in posterior lumbar fusion due to their ability to restore disc height and segmental alignment with minimal surgical exposure. However, concerns remain regarding their long-term durability, particularly the risk of implant subsidence. This study evaluates radiographic outcomes and subsidence rates over a 12-month period following posterior lumbar fusion with a novel expandable cage. We conducted a retrospective cohort study of 40 consecutive adult patients who underwent posterior lumbar fusion using a posteriorly placed expandable cage (Calibrate PSX) at a single academic institution. Radiographic parameters-including anterior disc height, posterior disc height, segmental lordosis, and global lumbar lordosis (L1-S1)-were measured preoperatively, immediately postoperatively, and at 3 and 12 months. Subsidence was graded according to the classification proposed by Levy et al. (2024). Generalized estimating equations were used for longitudinal analysis, with statistical significance set at p < 0.05. Among 44 implanted levels, 16 levels (36.4%) demonstrated subsidence at 3 months, increasing to 20 (45.5%) by 12 months. No surgical revisions were required at 12 months. Anterior disc height increased significantly in the immediate postoperative period (+ 8.6 mm, p < 0.0001) but declined over time, with greater loss in the subsidence group (-7.1 mm vs. - 1.9 mm, p = 0.013). Posterior disc height followed a similar trend. However, segmental and global lumbar lordosis remained stable, with no significant differences between subsidence and non-subsidence groups. Minor intraoperative complications occurred in 6 patients (13.6%) and resolved without sequelae. Expandable interbody cages provide substantial immediate postoperative improvements in disc height and alignment. While subsidence can occur over time, segmental and global lordosis are generally maintained. The overall subsidence rate was modest and not associated with adverse clinical outcomes. These findings support the cautious use of expandable cages in posterior lumbar fusion, with attention to patient selection, surgical technique and implant selection to mitigate the risk of subsidence.

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Journal
Neurosurgical Review
Published
2025-11-29
DOI
https://doi.org/10.1007/s10143-025-03943-x
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Radiographic assessment of segmental correction and subsidence following posterior lumbar fusion with expandable interbody cages: a 12-month retrospective cohort study

Hania Shahzad, Yashar Javidan, David A. Hsiou
Neurosurgical Review
Spine and Intervertebral Disc Pathology
article

Radiographic assessment of segmental correction and subsidence following posterior lumbar fusion with expandable interbody cages: a 12-month retrospective cohort study

Hania Shahzad, Yashar Javidan, David A. Hsiou
article en

Abstract

Expandable interbody cages have gained popularity in posterior lumbar fusion due to their ability to restore disc height and segmental alignment with minimal surgical exposure. However, concerns remain regarding their long-term durability, particularly the risk of implant subsidence. This study evaluates radiographic outcomes and subsidence rates over a 12-month period following posterior lumbar fusion with a novel expandable cage. We conducted a retrospective cohort study of 40 consecutive adult patients who underwent posterior lumbar fusion using a posteriorly placed expandable cage (Calibrate PSX) at a single academic institution. Radiographic parameters-including anterior disc height, posterior disc height, segmental lordosis, and global lumbar lordosis (L1-S1)-were measured preoperatively, immediately postoperatively, and at 3 and 12 months. Subsidence was graded according to the classification proposed by Levy et al. (2024). Generalized estimating equations were used for longitudinal analysis, with statistical significance set at p < 0.05. Among 44 implanted levels, 16 levels (36.4%) demonstrated subsidence at 3 months, increasing to 20 (45.5%) by 12 months. No surgical revisions were required at 12 months. Anterior disc height increased significantly in the immediate postoperative period (+ 8.6 mm, p < 0.0001) but declined over time, with greater loss in the subsidence group (-7.1 mm vs. - 1.9 mm, p = 0.013). Posterior disc height followed a similar trend. However, segmental and global lumbar lordosis remained stable, with no significant differences between subsidence and non-subsidence groups. Minor intraoperative complications occurred in 6 patients (13.6%) and resolved without sequelae. Expandable interbody cages provide substantial immediate postoperative improvements in disc height and alignment. While subsidence can occur over time, segmental and global lordosis are generally maintained. The overall subsidence rate was modest and not associated with adverse clinical outcomes. These findings support the cautious use of expandable cages in posterior lumbar fusion, with attention to patient selection, surgical technique and implant selection to mitigate the risk of subsidence.

Neurosurgical ReviewVol. 49(1)
St. Joseph Medical Center (US), University of California Davis Medical Center (US), UC Davis Health (US)
Openalex Percentile: Top 49%
Spine and Intervertebral Disc Pathology
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