Off-label prescribing in Italian pediatric practice: insights from a nationwide survey
• This nationwide Italian survey reveals that off-label prescribing in Italian pediatric hospitals is primarily driven by institutional specialization-especially NICU presence-rather than hospital size, with digital tracking and research units linked to better regulatory compliance. • A significant portion of facilities lack awareness of their off-label prescribing rates, highlighting the need for standardized oversight and national policy alignment to ensure safer pediatric drug use.
Authors
- Giulia Zamagni (ORCID: https://orcid.org/0000-0002-4949-3219)
- Antonio Arbo (ORCID: https://orcid.org/0000-0001-8937-580X)
- Francesca Rocchi (ORCID: https://orcid.org/0000-0002-4255-0823)
- Sergio Abbate (ORCID: https://orcid.org/0000-0001-9359-1214)
- Giovanni Migliore
- Anna Flamigni
Institutions
- Agenzia Regionale per la Protezione Ambientale del Piemonte (IT)
- IRCCS Materno Infantile Burlo Garofolo (IT)
- Agenzia Regionale Sanitaria della Puglia (IT)
- Bambino Gesù Children's Hospital (IT)
Publication Details
- Journal
- European Journal of Pediatrics
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1007/s00431-025-06660-1
- Primary Topic
- Pharmaceutical studies and practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ospedale Pediatrico Bambino Gesù
- Ministero della Salute
- Università degli Studi di Padova
- Istituto Ortopedico Rizzoli di Bologna