Van Wyk–Grumbach Syndrome With Insulin Resistance in Children: A Case Report
This case reports an 8 year-5 month-old girl diagnosed with Van Wyk-Grumbach Syndrome (VWGS) and co-existing insulin resistance from China. The patient achieved complete resolution of clinical manifestations with thyroid hormone replacement therapy. Pediatricians should raise awareness of this rare and underdiagnosed disorder to avoid unnecessary tumor investigations or surgical intervention.
Authors
- Gaojie Liu
- Hongfang Ding (ORCID: https://orcid.org/0000-0002-8603-824X)
- Weicai Suo
- Hui Wang (ORCID: https://orcid.org/0000-0002-2294-1085)
- Hui Liu (ORCID: https://orcid.org/0000-0003-0481-2607)
- Yizhong Wang (ORCID: https://orcid.org/0000-0002-9390-8864)
Institutions
- Shanghai Jiao Tong University (CN)
- Shengli Oilfield Central Hospital (CN)
- Shanghai Children's Hospital (CN)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1002/ccr3.71527
- Primary Topic
- Pectus Deformity Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China