FADS3 fuels ccRCC progression via lipid-droplet/TGF-β receptors axis bridging metabolic reprogramming and epithelial plasticity
Our study confirmed FADS3 as a key intermediate protein regulating fatty acid metabolism and tumor progression, which was expected to be a potential diagnostic and prognostic biomarker for ccRCC.
Authors
- Jiechuan Qiu (ORCID: https://orcid.org/0000-0003-0045-3811)
- Tianmin Yang
- Qinghua Xia (ORCID: https://orcid.org/0000-0002-4698-7889)
- Fan Peng
- Yanning Sun
- Haotian Ling (ORCID: https://orcid.org/0000-0003-3626-9397)
- Yuhu Hao
- Qingshun Bai (ORCID: https://orcid.org/0000-0002-8626-4431)
- Kai Sun (ORCID: https://orcid.org/0000-0003-4135-7412)
Institutions
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1097/js9.0000000000004094
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00