Adiposity and the first-onset of diagnosed mental illnesses: a population-based cohort study of 10 million UK adults
Individuals with severe obesity and underweight had increased risk of common and serious mental illnesses, especially in women, younger individuals, and Asian populations. Associations were not mediated by cardiometabolic diseases but partially by biomarkers.
Authors
- Paul Aveyard (ORCID: https://orcid.org/0000-0002-1802-4217)
- Joseph Firth (ORCID: https://orcid.org/0000-0002-0618-2752)
- Mika Kivimaki B (ORCID: https://orcid.org/0000-0002-4699-5627)
- Min Gao (ORCID: https://orcid.org/0000-0001-6196-7088)
- Cynthia Wright (ORCID: https://orcid.org/0000-0002-7196-1509)
- Shanquan Chen (ORCID: https://orcid.org/0000-0002-4724-4892)
- Dong Xue (ORCID: https://orcid.org/0000-0002-7269-6356)
- Xiaochen Yang (ORCID: https://orcid.org/0000-0001-7948-2249)
Institutions
- University of Helsinki (FI)
- Capital Medical University (CN)
- Peking University (CN)
- Manchester Academic Health Science Centre (GB)
- Warneford Hospital (GB)
- University of Manchester (GB)
- University of Oxford (GB)
- Beijing Anzhen Hospital (CN)
- University College London (GB)
- University of Hong Kong (HK)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-29
- DOI
- https://doi.org/10.1186/s12916-025-04514-z
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00