Suprachiasmatic Nuclei Possess Glucocorticoid Receptors That Activate Downstream Signaling Pathways but Do Not Entrain Their Circadian Clock
These results indicate that the adult SCN possesses GRs capable of activating GC-signaling pathways, but the clock is resistant to GC in part due to coupling between individual cellular oscillators.
Authors
- Vendula Lužná
- Martin Sládek (ORCID: https://orcid.org/0000-0002-9744-9386)
- Alena Sumová (ORCID: https://orcid.org/0000-0003-4126-5470)
- Pavel Houdek (ORCID: https://orcid.org/0000-0002-0746-9384)
Institutions
- Czech Academy of Sciences (CZ)
- Czech Academy of Sciences, Institute of Physiology (CZ)
Publication Details
- Journal
- Acta Physiologica
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1111/apha.70138
- Citations
- 1
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Grantová Agentura České Republiky