Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency–a cross-sectional study

In this convenience sample of young women in Switzerland, one in five was iron deficient and one in 30 was anemic due to iron deficiency. Controlling ferritin concentrations for inflammation did not substantially affect the prevalence of iron deficiency, indicating that such corrections are redundant in a healthy population with a low prevalence of inflammation. Impaired erythropoiesis was observed when the ferritin concentration fell below 28.5 µg/l, providing further evidence for a physiologically based ferritin threshold to identify the onset of iron-deficient erythropoiesis.

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Publication Details

Journal
European Journal of Clinical Nutrition
Published
2025-11-28
DOI
https://doi.org/10.1038/s41430-025-01685-z
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency–a cross-sectional study

Valeria Galetti, Maria Andersson, Isabelle Herter‐Aeberli
European Journal of Clinical Nutrition
Iron Metabolism and Disorders
article

Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency–a cross-sectional study

Valeria Galetti, Maria Andersson, Isabelle Herter‐Aeberli
article en

Abstract

In this convenience sample of young women in Switzerland, one in five was iron deficient and one in 30 was anemic due to iron deficiency. Controlling ferritin concentrations for inflammation did not substantially affect the prevalence of iron deficiency, indicating that such corrections are redundant in a healthy population with a low prevalence of inflammation. Impaired erythropoiesis was observed when the ferritin concentration fell below 28.5 µg/l, providing further evidence for a physiologically based ferritin threshold to identify the onset of iron-deficient erythropoiesis.

European Journal of Clinical NutritionVol. 80(2)
ETH Zurich (CH), University Children's Hospital Zurich (CH)
Eidgenössische Technische Hochschule Zürich
Openalex Percentile: Top 51%
Iron Metabolism and Disorders
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Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency–a cross-sectional study — Valeria Galetti, Maria Andersson, et al. · European Journal of Clinical Nutrition (2025) | TGRS Research Map | TGRS