Suppressor of cytokine signaling 2 is associated with growth impairment in pediatric chronic kidney disease
Circulating SOCS2 levels are elevated in pediatric CKD and independently associated with growth impairment, suggesting its potential link to GH resistance, which is typical of CKD. SOCS2 might be a potential new marker of growth retardation. Further longitudinal studies are needed to explore its predictive value for longitudinal growth and GH treatment response.
Authors
- Anna Deja (ORCID: https://orcid.org/0000-0002-9901-4140)
- Beata Leszczyńska (ORCID: https://orcid.org/0000-0001-6811-4934)
- Małgorzata Pańczyk-Tomaszewska (ORCID: https://orcid.org/0000-0002-4566-7074)
- Anna Stelmaszczyk‐Emmel (ORCID: https://orcid.org/0000-0003-3667-1220)
- Maja Wujec
- Nikola Materny
Institutions
- Medical University of Warsaw (PL)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1007/s00467-025-07029-0
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00