Shoulder Injury Related to Vaccine Administration (SIRVA) After COVID-19 Vaccination: A Retrospective Study

SIRVA is a rare complication following COVID-19 vaccination and is best considered a medicolegal term rather than a definitive diagnosis. Strict adherence to diagnostic criteria is essential, as overdiagnosis may occur among patients with coincidental post-vaccination shoulder pain. While most cases resolve with conservative management, a subset may experience persistent symptoms. Evidence suggests that SIRVA is more likely related to improper injection technique rather than the vaccine itself.

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Publication Details

Journal
Cureus
Published
2025-11-28
DOI
https://doi.org/10.7759/cureus.98023
Primary Topic
Intramuscular injections and effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Shoulder Injury Related to Vaccine Administration (SIRVA) After COVID-19 Vaccination: A Retrospective Study

Matthew Smith, Gopikanthan Manoharan, Peter Brownson, J.R. Winton et al.
Cureus
Intramuscular injections and effects
article

Shoulder Injury Related to Vaccine Administration (SIRVA) After COVID-19 Vaccination: A Retrospective Study

Matthew Smith, Gopikanthan Manoharan, Peter Brownson, J.R. Winton, Thivagar Murugesan
article en

Abstract

SIRVA is a rare complication following COVID-19 vaccination and is best considered a medicolegal term rather than a definitive diagnosis. Strict adherence to diagnostic criteria is essential, as overdiagnosis may occur among patients with coincidental post-vaccination shoulder pain. While most cases resolve with conservative management, a subset may experience persistent symptoms. Evidence suggests that SIRVA is more likely related to improper injection technique rather than the vaccine itself.

CureusVol. 17(11)
University of Liverpool (GB), Aintree University Hospitals NHS Foundation Trust (GB), Royal Shrewsbury Hospital (GB), Robert Jones and Agnes Hunt Orthopaedic Hospital (GB), Shrewsbury and Telford Hospital NHS Trust (GB), Liverpool Womens NHS Foundation Trust (GB)
Openalex Percentile: Top 47%
Intramuscular injections and effects
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Shoulder Injury Related to Vaccine Administration (SIRVA) After COVID-19 Vaccination: A Retrospective Study — Matthew Smith, Gopikanthan Manoharan, et al. · Cureus (2025) | TGRS Research Map | TGRS