Metarhizium pingshaense infection reverses insecticide resistance in Anopheles gambiae sensu lato by altering energy reserves and gene expression
We demonstrate that Metarhizium infection reverses insecticide resistance in An. gambiae s.l. by depleting energy reserves and suppressing the expression of detoxification genes. This mechanistic insight is crucial for optimizing the future integration of Metarhizium alongside conventional insecticides for malaria vector control.
Authors
- Moussa Namountougou (ORCID: https://orcid.org/0000-0002-6560-218X)
- Doubé Lucien Lamy
- Mafalda Viana (ORCID: https://orcid.org/0000-0001-5975-6505)
- Najat F. Kahamba (ORCID: https://orcid.org/0000-0002-4471-5820)
- Duangkamon Loesbanluechai (ORCID: https://orcid.org/0009-0006-5547-9778)
- Abdoulaye Diabaté (ORCID: https://orcid.org/0000-0002-9666-9395)
- Issiaka Saré (ORCID: https://orcid.org/0000-0003-4216-134X)
- Etienne Bilgo (ORCID: https://orcid.org/0000-0003-2350-9339)
- Francesco Baldini (ORCID: https://orcid.org/0000-0002-2689-5952)
- Edounou Jacques Gnambani (ORCID: https://orcid.org/0000-0003-4515-046X)
- Souro Abel Millogo
- Iván Casas Gómez-Uribarri (ORCID: https://orcid.org/0009-0004-8017-2079)
- Erin S. Johnston
- Meshach Lee
Institutions
- Ifakara Health Institute (TZ)
- Université Joseph Ki-Zerbo (BF)
- Nazi Boni University (BF)
- Centre Muraz (BF)
- Institut de Recherche en Sciences de la Santé (BF)
- University of Glasgow (GB)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s13071-025-07132-z
- Primary Topic
- Entomopathogenic Microorganisms in Pest Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00