Mitochondrial DNA Damage and Inflammatory Markers in Bronchoalveolar Lavage Fluid during Acute Exacerbations of Bronchiectasis

mtDNA damage and elevated inflammatory marker levels in BALF are closely associated with AEs of bronchiectasis. These findings highlight their potential as biomarkers and therapeutic targets for future clinical application. Further studies are warranted to validate these observations and explore their role in the clinical management of bronchiectasis.

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Publication Details

Journal
International Archives of Allergy and Immunology
Published
2025-11-28
DOI
https://doi.org/10.1159/000549730
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
0.00
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article

Mitochondrial DNA Damage and Inflammatory Markers in Bronchoalveolar Lavage Fluid during Acute Exacerbations of Bronchiectasis

Weiping Yuan, Jiamin Xie, Lichong Chen, Shodhan Rao et al.
International Archives of Allergy and Immunology
Cystic Fibrosis Research Advances
article

Mitochondrial DNA Damage and Inflammatory Markers in Bronchoalveolar Lavage Fluid during Acute Exacerbations of Bronchiectasis

Weiping Yuan, Jiamin Xie, Lichong Chen, Shodhan Rao, Huafeng Li, Wanwen Liang, Chenli Xie
article en

Abstract

mtDNA damage and elevated inflammatory marker levels in BALF are closely associated with AEs of bronchiectasis. These findings highlight their potential as biomarkers and therapeutic targets for future clinical application. Further studies are warranted to validate these observations and explore their role in the clinical management of bronchiectasis.

International Archives of Allergy and Immunology
Dongguan University of Technology (CN), Dongguan People’s Hospital (CN)
Openalex Percentile: Top 44%
Cystic Fibrosis Research Advances
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