Functional ability in cognitive complaints: The role of neuropsychiatric and cognitive factors in community‐dwelling older adults
Abstract INTROCUTION The relationship between functional ability and neuropsychiatric or cognitive factors in older adults with cognitive complaints (CCs) remains unexplored in Latin America. METHODS Two hundred ninety community‐dwelling older adults with CCs were recruited. Multiple regression analyzed the association between activities of daily living (ADLs) and neuropsychiatric and cognitive factors. Variance proportion in ADLs were further explored. RESULTS Apathy was associated with reduced functional ability (Technology‐Activities of Daily Living Questionnaire [T‐ADLQ] global score [ β = −0.42, 95% confidence interval [CI] [−0.57, −0.28]). Depression was linked to impaired advanced ADLs ( β = 0.94, 95% CI [0.09, 1.79]) and basic ADLs ( β = 0.22, 95% CI [0.03, 0.42]). Naming and speeded processing were significantly associated with global ADLs ( β = −0.55, 95% CI [−0.99, −0.12]; β = 0.26, 95% CI [0.04, 0.48], respectively) and distinct ADLs sub‐scores. DISCUSSION Neuropsychiatric and cognitive factors affect ADLs based on their complexity. These results call for targeted interventions supporting independence in Latin American older adults.
Authors
- Agustín M. Ibáñez (ORCID: https://orcid.org/0000-0001-6758-5101)
- David Martínez‐Pernía (ORCID: https://orcid.org/0000-0003-2830-7920)
- Mauricio Cerda (ORCID: https://orcid.org/0000-0003-3447-1815)
- Gonzalo Forno (ORCID: https://orcid.org/0000-0003-2739-6028)
- Daniela Thumala (ORCID: https://orcid.org/0000-0003-0392-7031)
- Fernando Henríquez (ORCID: https://orcid.org/0000-0001-9854-9680)
- Pedro Zitko (ORCID: https://orcid.org/0000-0003-1162-4591)
- Andrea Slachevsky (ORCID: https://orcid.org/0000-0001-6285-3189)
- Patricia Lillo (ORCID: https://orcid.org/0000-0001-7398-7203)
- Maureen Schmitter‐Edgecombe (ORCID: https://orcid.org/0000-0002-5304-2146)
- Adolfo M. García (ORCID: https://orcid.org/0000-0002-6936-0114)
- Eneida Mioshi (ORCID: https://orcid.org/0000-0002-0066-868X)
- Michael Homberger
Institutions
- Universidad de Santiago de Chile (CL)
- University of East Anglia (GB)
- Pontificia Universidad Católica de Chile (CL)
- Trinity College Dublin (IE)
- Adolfo Ibáñez University (CL)
- Clínica Alemana (CL)
- University of San Andrés (AR)
- Hospital del Salvador (CL)
- Instituto de Neurociencia Biomédica (CL)
- Center for Climate and Resilience Research (CL)
- Global Brain Health Institute (US)
- Millennium Institute for Integrative Biology (CL)
- University of Southampton (GB)
- University of Chile (CL)
- Washington State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia Behavior & Socioeconomics of Aging
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1002/bsa3.70051
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47