Systemic sclerosis: bridging clinical and molecular insights: results from the PRECISESADS study
Unsupervised clustering and proteomic profiling reveal biologically distinct subgroups within SSc, beyond traditional clinical or serological classifications. Our findings support the integration of molecular tools into patient stratification strategies, paving the way toward personalized medicine in SSc.
Authors
- Clementina López‐Medina (ORCID: https://orcid.org/0000-0002-2309-5837)
- R. Ortega Castro (ORCID: https://orcid.org/0000-0002-7552-3469)
- C. Pérez‐Sánchez (ORCID: https://orcid.org/0000-0002-1903-5970)
- C. López-Pedrera (ORCID: https://orcid.org/0000-0003-2067-4603)
- Alejandro Escudero‐Contreras (ORCID: https://orcid.org/0000-0001-5891-5527)
- S. Dans-Caballero (ORCID: https://orcid.org/0009-0002-8529-0125)
- Beatriz Vellón-García
Institutions
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Hospital Universitario Reina Sofía (ES)
- University of Córdoba (ES)
- Cordoba University (US)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s12967-025-07469-0
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00