Quality of life and late toxicity after total neoadjuvant treatment for locally advanced rectal cancer – LARCT-US

An abbreviated TNT schedule, compared with the RAPIDO-study, used in LARCT-US, achieves favourable oncological outcomes with low risk of late toxicity, and an acceptable QoL similar to other less effective neoadjuvant treatments.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2025-11-28
DOI
https://doi.org/10.1016/j.radonc.2025.111318
Citations
3
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
3.14
Controls
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article

Quality of life and late toxicity after total neoadjuvant treatment for locally advanced rectal cancer – LARCT-US

Per J. Nilsson, Israa Imam, Bengt Glimelius, Tanweera Khan
3 citations
Radiotherapy and Oncology
Colorectal Cancer Surgical Treatments
3.14
article

Quality of life and late toxicity after total neoadjuvant treatment for locally advanced rectal cancer – LARCT-US

Per J. Nilsson, Israa Imam, Bengt Glimelius, Tanweera Khan
article en
3 citations

Abstract

An abbreviated TNT schedule, compared with the RAPIDO-study, used in LARCT-US, achieves favourable oncological outcomes with low risk of late toxicity, and an acceptable QoL similar to other less effective neoadjuvant treatments.

Radiotherapy and OncologyVol. 214
Karolinska University Hospital (SE), Uppsala University Hospital (SE)
Openalex Percentile: Top 7%
Colorectal Cancer Surgical Treatments
3.14
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