Exercise as a treatment for hypertension: Literature review

<ns3:p>Hypertension, or high blood pressure, can result in severe complications such as heart attacks and strokes. Hypertension doubles the risk of developing cardiovascular diseases, such as coronary heart disease, congestive heart failure, ischemic and hemorrhagic stroke, renal failure, and peripheral arterial disease. Although the exact cause of primary hypertension remains unclear, many risk factors are strongly and independently associated with its development. In contrast, risk factors for secondary hypertension can overlap with those for primary hypertension, presenting significant challenges in maintaining proper blood pressure control. Most individuals with hypertension do not exhibit any symptoms. However, extremely high blood pressure can cause headaches, blurred vision, chest pain, and other symptoms. Multiple studies have shown that physical activity lowers blood pressure regardless of weight loss, benefiting both individuals with normal blood pressure and those with hypertension. The exact molecular mechanisms responsible for the beneficial effects of physical activity on blood pressure remain largely unknown, likely due to the complex and multifaceted nature of blood pressure regulation, involving neuro-hormonal, hemodynamic, and metabolic factors. Clinicians should incorporate practical strategies into exercise prescriptions, such as working out with friends, joining community groups, and tracking physical activity duration or counts.</ns3:p>

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Publication Details

Journal
F1000Research
Published
2025-11-28
DOI
https://doi.org/10.12688/f1000research.172553.1
Primary Topic
Cardiovascular and exercise physiology
Type
article
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article

Exercise as a treatment for hypertension: Literature review

Telila Mesfin, Olifan Getachew
F1000Research
Cardiovascular and exercise physiology
article

Exercise as a treatment for hypertension: Literature review

Telila Mesfin, Olifan Getachew
article en

Abstract

<ns3:p>Hypertension, or high blood pressure, can result in severe complications such as heart attacks and strokes. Hypertension doubles the risk of developing cardiovascular diseases, such as coronary heart disease, congestive heart failure, ischemic and hemorrhagic stroke, renal failure, and peripheral arterial disease. Although the exact cause of primary hypertension remains unclear, many risk factors are strongly and independently associated with its development. In contrast, risk factors for secondary hypertension can overlap with those for primary hypertension, presenting significant challenges in maintaining proper blood pressure control. Most individuals with hypertension do not exhibit any symptoms. However, extremely high blood pressure can cause headaches, blurred vision, chest pain, and other symptoms. Multiple studies have shown that physical activity lowers blood pressure regardless of weight loss, benefiting both individuals with normal blood pressure and those with hypertension. The exact molecular mechanisms responsible for the beneficial effects of physical activity on blood pressure remain largely unknown, likely due to the complex and multifaceted nature of blood pressure regulation, involving neuro-hormonal, hemodynamic, and metabolic factors. Clinicians should incorporate practical strategies into exercise prescriptions, such as working out with friends, joining community groups, and tracking physical activity duration or counts.</ns3:p>

F1000ResearchVol. 14
Madda Walabu University (ET), Haramaya University (ET)
Openalex Percentile: Top 46%
Cardiovascular and exercise physiology
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Exercise as a treatment for hypertension: Literature review — Telila Mesfin, Olifan Getachew · F1000Research (2025) | TGRS Research Map | TGRS