Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway
This study demonstrates that Sesn2 inhibits ferroptosis in LPS-treated H9c2 cells through the Nrf2/HO-1 pathway, and also exerts an anti-apoptotic effect.
Authors
- Qingshan Tian
- Yiheng Yang (ORCID: https://orcid.org/0000-0001-8053-9871)
- Zhenzhong Zheng (ORCID: https://orcid.org/0000-0001-9239-3996)
- Peng Yang
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s40001-025-03580-6
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00