Association among persistent chemical pollutants and infectious encephalitis: a mixture exposure and mediation approach

We found that most persistent chemical pollutants in the air increase the risk of neurotoxicity-related morbidity and mortality. Among them, epidemic cerebrospinal meningitis is primarily driven by PCB and OC, while encephalitis B is mainly driven by CH<sub>4</sub> and HCB. The greenhouse gas N<sub>2</sub>O may play a mediating role between chemical pollutant exposure and the outcomes of infectious encephalitis. In the future, identifying the effects of chemical mixtures can better support the causal relationship between air pollution and neurotoxicity.

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Publication Details

Journal
BMC Public Health
Published
2025-11-28
DOI
https://doi.org/10.1186/s12889-025-25768-5
Primary Topic
Air Quality and Health Impacts
Type
article
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article

Association among persistent chemical pollutants and infectious encephalitis: a mixture exposure and mediation approach

Weimin Hou, Zhenyao Song, Juan Han, G L Qu
BMC Public Health
Air Quality and Health Impacts
article

Association among persistent chemical pollutants and infectious encephalitis: a mixture exposure and mediation approach

Weimin Hou, Zhenyao Song, Juan Han, G L Qu
article en

Abstract

We found that most persistent chemical pollutants in the air increase the risk of neurotoxicity-related morbidity and mortality. Among them, epidemic cerebrospinal meningitis is primarily driven by PCB and OC, while encephalitis B is mainly driven by CH<sub>4</sub> and HCB. The greenhouse gas N<sub>2</sub>O may play a mediating role between chemical pollutant exposure and the outcomes of infectious encephalitis. In the future, identifying the effects of chemical mixtures can better support the causal relationship between air pollution and neurotoxicity.

BMC Public HealthVol. 25(1)
United States Air Force (US), Air Force General Hospital PLA (CN)
Openalex Percentile: Top 54%
Air Quality and Health Impacts
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