The Effect of Increased Sodium Intake with a Carbohydrate-Rich Meal on Glucose Homeostasis in People without Diabetes after Roux-en-Y Gastric Bypass: a Proof-of-Concept, Randomized, Open-Label, Crossover Study
In individuals post-RYGB without diabetes, sodium supplementation during a carbohydrate-rich meal did not substantially affect glucose homeostasis, although it appeared to reduce peak postprandial plasma glucose. Further studies are warranted to explore the clinical relevance of this effect.
Authors
- Joseph J. Henson (ORCID: https://orcid.org/0000-0002-3898-7053)
- David J. Bowrey (ORCID: https://orcid.org/0000-0003-4265-7118)
- Gráinne Whelehan (ORCID: https://orcid.org/0000-0003-1391-4349)
- Dimitris Papamargaritis (ORCID: https://orcid.org/0000-0001-5044-1515)
- Alice E. Thackray (ORCID: https://orcid.org/0000-0002-7800-3207)
- Alan Askari (ORCID: https://orcid.org/0000-0001-5993-7613)
- Oluwaseun Anyiam (ORCID: https://orcid.org/0000-0003-2425-2299)
- David R. Webb (ORCID: https://orcid.org/0000-0002-3932-3339)
- Anjali Zalin
- David J. Stensel (ORCID: https://orcid.org/0000-0001-9119-8590)
- Louisa Herring (ORCID: https://orcid.org/0000-0002-9592-6759)
- Melanie Jane Davies (ORCID: https://orcid.org/0000-0002-9987-9371)
- Iskander Idris
- Tom Yates (ORCID: https://orcid.org/0000-0002-6081-1767)
- Stanislava Katsarova–Harrison
Institutions
- Loughborough University (GB)
- Waseda University (JP)
- University of Leicester (GB)
- Luton and Dunstable University Hospital NHS Foundation Trust (GB)
- Leicester General Hospital (GB)
- Kettering General Hospital (GB)
- Leicester College (GB)
- University Hospitals of Leicester NHS Trust (GB)
- University Hospitals of Derby and Burton NHS Foundation Trust (GB)
- NIHR Leicester Biomedical Research Centre (GB)
- Kettering General Hospital NHS Trust (GB)
Publication Details
- Journal
- Obesity Surgery
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1007/s11695-025-08420-4
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- NIHR Leicester Biomedical Research Centre