Cs <sub>2</sub> CO <sub>3</sub> ‐Promoted Hydrothiolation of <i>N</i> ‐Arylpropiolamides With Thiophenols Toward Thioalkenyl Amides
ABSTRACT Herein, a Cs 2 CO 3 ‐promoted hydrothiolation of N‐arylpropiolamides with thiophenols has been accomplished. A series of substituted N ‐arylpropiolamides and thiophenols participated smoothly in this reaction, affording various functionalized thioalkenyl amides in moderate to good yields under transition‐metal‐free conditions. This method features a broad substrate scope and operational simplicity.
Authors
- Hongni Qin
- Yong Zhang (ORCID: https://orcid.org/0000-0001-7207-6416)
- Fan Wu (ORCID: https://orcid.org/0000-0001-7686-2887)
- Yuzhen Xie
- Song Sun (ORCID: https://orcid.org/0000-0002-9974-6456)
Institutions
- Suzhou Polytechnic Institute of Agriculture (CN)
- Changzhou University (CN)
- Suzhou Industrial Park Institute of Services Outsourcing (CN)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1002/slct.202507046
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Changzhou University
- Natural Environment Research Council
- HORIZON EUROPE Excellent Science