Melanosis Coli Associated with SAPHO Syndrome: A Rare Coexistence Suggesting a Possible Gut–Bone Axis Link

Abs tractWe report the incidental detection of melanosis coli during a colonoscopy in a 72-year-old man with a history of laxative use.Subsequent imaging supported a diagnosis of SAPHO syndrome.The co-occurrence of these conditions is rare, and its clinical significance remains uncertain.This report aims to discuss potential underlying mechanisms, diagnostic challenges, and therapeutic considerations.

Authors

Publication Details

Journal
Medical Bulletin of Haseki
Published
2025-11-28
DOI
https://doi.org/10.4274/haseki.galenos.2025.84756
Primary Topic
Osteomyelitis and Bone Disorders Research
Type
article
Field-Weighted Citation Impact
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article

Melanosis Coli Associated with SAPHO Syndrome: A Rare Coexistence Suggesting a Possible Gut–Bone Axis Link

Chendong He, Wei Yang
Medical Bulletin of Haseki
Osteomyelitis and Bone Disorders Research
article

Melanosis Coli Associated with SAPHO Syndrome: A Rare Coexistence Suggesting a Possible Gut–Bone Axis Link

Chendong He, Wei Yang
article en

Abstract

Abs tractWe report the incidental detection of melanosis coli during a colonoscopy in a 72-year-old man with a history of laxative use.Subsequent imaging supported a diagnosis of SAPHO syndrome.The co-occurrence of these conditions is rare, and its clinical significance remains uncertain.This report aims to discuss potential underlying mechanisms, diagnostic challenges, and therapeutic considerations.

Medical Bulletin of HasekiVol. 63(5)
Openalex Percentile: Top 47%
Osteomyelitis and Bone Disorders Research
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Melanosis Coli Associated with SAPHO Syndrome: A Rare Coexistence Suggesting a Possible Gut–Bone Axis Link — Chendong He, Wei Yang · Medical Bulletin of Haseki (2025) | TGRS Research Map | TGRS