Association between the hemoglobin, albumin, lymphocyte, and platelet (HALP) score and 28-day mortality in neurocritical care patients: a retrospective cohort study based on the MIMIC-IV database
Our findings are consistent with an inverse association between HALP scores and short-term survival in neurocritical care patients. With a modest predictive discrimination (AUC ≤ 0.73), this scoring system may have potential as a complementary clinical risk assessment tool. Future validation is warranted to confirm its utility in aiding the risk stratification of neurocritical care patients.
Authors
- Min Shao (ORCID: https://orcid.org/0000-0002-6922-0445)
- Yajun Zou (ORCID: https://orcid.org/0000-0001-9823-1488)
- Jianlin Zhang (ORCID: https://orcid.org/0000-0001-5390-8088)
- Zhipeng Wang (ORCID: https://orcid.org/0000-0002-7964-9288)
- Xia Yu (ORCID: https://orcid.org/0000-0001-6983-1847)
- Yuxin Chen (ORCID: https://orcid.org/0000-0001-5955-687X)
- Teng Long (ORCID: https://orcid.org/0000-0003-4401-102X)
- Li Hu (ORCID: https://orcid.org/0000-0002-6657-4707)
Institutions
- Wannan Medical College (CN)
- Shandong University of Aeronautics (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- PLA Navy General Hospital (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s40001-025-03437-y
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Anhui Medical University
- University Natural Science Research Project of Anhui Province