Influenza vaccination and ischemic stroke risk reduction in elderly stroke survivors: a retrospective cohort study with negative control validation
Influenza vaccination is associated with lower ischemic stroke risk among elderly stroke survivors, independent of cardiogenic etiology. These findings suggest a potential nonspecific preventive benefit and highlight the need for randomized trials to establish causality and inform clinical guidelines for stroke survivors.
Authors
- Huan Yang (ORCID: https://orcid.org/0000-0001-6422-8643)
- Lixia Ye (ORCID: https://orcid.org/0000-0002-6201-3224)
- Tianshu Zhou (ORCID: https://orcid.org/0000-0002-5858-6353)
- Xiaoqing Wu (ORCID: https://orcid.org/0000-0003-2076-4107)
- Tianchi Yang (ORCID: https://orcid.org/0000-0002-9971-5107)
Institutions
- Ningbo University (CN)
- Henan University (CN)
- Wenzhou Medical University (CN)
- Ningbo Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s12877-025-06695-x
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhejiang Province Public Welfare Technology Application Research Project