Patient characteristics, disease manifestations and diagnostic findings of consecutive patients suspected of Giant Cell Arteritis (GCA) — retrospective experience from a fast-track clinic in Israel

The GCAPS is a reliable tool for risk-stratifying patients referred to the GCA-FTC in this study population. The sensitivity and specificity of CDUS was 90.9% and 88%, respectively. A relatively low prevalence of large vessel involvement was documented. Our results suggest that rheumatologists should remain vigilant regarding the differential diagnoses in patients with suspected GCA. Key Points • Our study is the first study in the Middle East to utilize color-Doppler ultrasonography (CDUS) in Giant Cell Arteritis Fast Track Clinic (GCA-FTC) setting, and it was found to have very high sensitivity (90.9) and specificity (88.0%). • In our study population, the Southend Pre-Test Probability Score for GCA (GCAPS) was found to be a reliable tool for risk- stratifying patients referred to the GCA-FTC. • Based on our findings, rheumatologists should remain vigilant regarding the differential diagnoses of patients with suspected GCA, including pure PMR, migraine headache, infection, CPPD and TMJ dysfunction.

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Publication Details

Journal
Clinical Rheumatology
Published
2025-11-27
DOI
https://doi.org/10.1007/s10067-025-07787-0
Primary Topic
Vasculitis and related conditions
Type
article
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article

Patient characteristics, disease manifestations and diagnostic findings of consecutive patients suspected of Giant Cell Arteritis (GCA) — retrospective experience from a fast-track clinic in Israel

Devy Zisman, Joy Feld, Naomi Finkelstein, Ameen Batheesh et al.
Clinical Rheumatology
Vasculitis and related conditions
article

Patient characteristics, disease manifestations and diagnostic findings of consecutive patients suspected of Giant Cell Arteritis (GCA) — retrospective experience from a fast-track clinic in Israel

Devy Zisman, Joy Feld, Naomi Finkelstein, Ameen Batheesh, Tal Gazitt, Muhanad Abu Elhija, Amir Haddad, Muna Elias, Noa Hayat
article en

Abstract

The GCAPS is a reliable tool for risk-stratifying patients referred to the GCA-FTC in this study population. The sensitivity and specificity of CDUS was 90.9% and 88%, respectively. A relatively low prevalence of large vessel involvement was documented. Our results suggest that rheumatologists should remain vigilant regarding the differential diagnoses in patients with suspected GCA. Key Points • Our study is the first study in the Middle East to utilize color-Doppler ultrasonography (CDUS) in Giant Cell Arteritis Fast Track Clinic (GCA-FTC) setting, and it was found to have very high sensitivity (90.9) and specificity (88.0%). • In our study population, the Southend Pre-Test Probability Score for GCA (GCAPS) was found to be a reliable tool for risk- stratifying patients referred to the GCA-FTC. • Based on our findings, rheumatologists should remain vigilant regarding the differential diagnoses of patients with suspected GCA, including pure PMR, migraine headache, infection, CPPD and TMJ dysfunction.

Clinical RheumatologyVol. 45(2)
Technion – Israel Institute of Technology (IL), Carmel Medical Center (IL)
Openalex Percentile: Top 45%
Vasculitis and related conditions
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