Methadone and morphine have equivalent analgesic but not reward potency in female mice

These findings demonstrate that methadone has a lower reward, but similar analgesic potency compared to morphine in female mice.

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Publication Details

Journal
Addiction Neuroscience
Published
2025-09-24
DOI
https://doi.org/10.1016/j.addicn.2025.100238
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
0.00
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article

Methadone and morphine have equivalent analgesic but not reward potency in female mice

Sergi Ferré, Michael A. Kelberman, Akash Shanmugam, Samantha O. Vanderhoof et al.
Addiction Neuroscience
Neurotransmitter Receptor Influence on Behavior
article

Methadone and morphine have equivalent analgesic but not reward potency in female mice

Sergi Ferré, Michael A. Kelberman, Akash Shanmugam, Samantha O. Vanderhoof, Katharine E. McCann, David Weinshenker
article en

Abstract

These findings demonstrate that methadone has a lower reward, but similar analgesic potency compared to morphine in female mice.

Addiction NeuroscienceVol. 17
National Institutes of Health (US), National Institute on Drug Abuse (US), Emory University (US), University of Colorado Boulder (US)
Openalex Percentile: Top 60%
Neurotransmitter Receptor Influence on Behavior
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