Identification of a novel diagnostic biomarker for osteoarthritis associated with chromatin regulators based on bioinformatics and experiments

Our findings suggest that AURKB serves as a crucial biomarker in the development and progression of OA and is significantly associated with immune infiltration, offering a novel perspective for elucidating the pathogenesis of OA.

Authors

Institutions

Publication Details

Journal
Journal of Orthopaedic Surgery and Research
Published
2025-11-28
DOI
https://doi.org/10.1186/s13018-025-06493-6
Citations
1
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
1.67
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Identification of a novel diagnostic biomarker for osteoarthritis associated with chromatin regulators based on bioinformatics and experiments

Hao Xu, Shuihua Xie, Xinyu Wang, Jun Wu et al.
1 citations
Journal of Orthopaedic Surgery and Research
Rheumatoid Arthritis Research and Therapies
1.67
article

Identification of a novel diagnostic biomarker for osteoarthritis associated with chromatin regulators based on bioinformatics and experiments

Hao Xu, Shuihua Xie, Xinyu Wang, Jun Wu, Jiakang Chen
article en
1 citations

Abstract

Our findings suggest that AURKB serves as a crucial biomarker in the development and progression of OA and is significantly associated with immune infiltration, offering a novel perspective for elucidating the pathogenesis of OA.

Journal of Orthopaedic Surgery and ResearchVol. 20(1)
Integrated Chinese Medicine (China) (HK)
Openalex Percentile: Top 11%
Rheumatoid Arthritis Research and Therapies
1.67
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.