Booster dose reshapes SARS-CoV-2 RBD-specific B cell immunity in people living with HIV
These findings highlight the impact of boosting, particularly the third dose, in enhancing and shaping the RBD-specific MBC in PLWH. Clinical and demographic variables associated with long-term MBC persistence may serve as potential biomarkers for predicting durable vaccine responses in PLWH.
Authors
- Jacopo Polvere (ORCID: https://orcid.org/0000-0002-8345-0546)
- Simone Lucchesi (ORCID: https://orcid.org/0000-0003-3545-7433)
- Donata Medaglini (ORCID: https://orcid.org/0000-0003-1729-7325)
- Giorgio Montesi (ORCID: https://orcid.org/0000-0002-9054-2756)
- Massimiliano Fabbiani (ORCID: https://orcid.org/0000-0002-1343-812X)
- Fabio Fiorino (ORCID: https://orcid.org/0000-0002-1440-8061)
- Mario Tumbarello (ORCID: https://orcid.org/0000-0002-9519-8552)
- G Pastore (ORCID: https://orcid.org/0000-0002-3219-6170)
- Annalisa Ciabattini (ORCID: https://orcid.org/0000-0002-4585-7783)
- Francesca Montagnani (ORCID: https://orcid.org/0000-0002-2267-1337)
Institutions
- University of Siena (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s12967-025-07414-1
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- European Commission