Radiotherapy with 5 × 5 Gy for Personalized Treatment of Malignant Epidural Compression of the Myelon: Long-Term Results of the PRE-MODE Trial

Since 5 × 5 Gy resulted in excellent long-term LPFS and showed a trend towards better outcomes up to 24 months following RT, it appears preferable to 5 × 4 Gy and will contribute to the personalized treatment of patients with MESCC who are assigned to RT alone without upfront neurosurgical intervention.

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Publication Details

Journal
Journal of Personalized Medicine
Published
2025-11-28
DOI
https://doi.org/10.3390/jpm15120577
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
Field-Weighted Citation Impact
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article

Radiotherapy with 5 × 5 Gy for Personalized Treatment of Malignant Epidural Compression of the Myelon: Long-Term Results of the PRE-MODE Trial

Blaž Grošelj, Antonio J. Conde-Moreno, R. Ciérvide, C. Ferrer Albiach et al.
Journal of Personalized Medicine
Cervical and Thoracic Myelopathy
article

Radiotherapy with 5 × 5 Gy for Personalized Treatment of Malignant Epidural Compression of the Myelon: Long-Term Results of the PRE-MODE Trial

Blaž Grošelj, Antonio J. Conde-Moreno, R. Ciérvide, C. Ferrer Albiach, Jon Cacicedo, Barbara Šegedin, Darejan Lomidze, Dirk Rades
article en

Abstract

Since 5 × 5 Gy resulted in excellent long-term LPFS and showed a trend towards better outcomes up to 24 months following RT, it appears preferable to 5 × 4 Gy and will contribute to the personalized treatment of patients with MESCC who are assigned to RT alone without upfront neurosurgical intervention.

Journal of Personalized MedicineVol. 15(12)
University of Ljubljana (SI), Hospital Universitari i Politècnic La Fe (ES), Institute of Oncology Ljubljana (SI), BioCruces Health research Institute (ES), Consorcio Hospitalario Provincial de Castellón (ES), Hospital de Cruces (ES), Hospital Universitario HM Sanchinarro (ES), Tbilisi State Medical University (GE), University of Lübeck (DE)
Openalex Percentile: Top 44%
Cervical and Thoracic Myelopathy
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