Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen

Our study uncovers the multi-scale principles of nuclear organization in a major fungal plant pathogen and reveals how hierarchical nuclear architecture contributes to gene expression coordination and genome stability. These findings establish a conceptual framework for investigating 3D genome function and chromatin-mediated regulation in filamentous fungi and other eukaryotic microbes.

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Publication Details

Journal
BMC Biology
Published
2025-11-28
DOI
https://doi.org/10.1186/s12915-025-02461-y
Citations
1
Primary Topic
Genomics and Chromatin Dynamics
Type
article
Field-Weighted Citation Impact
0.81

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article

Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen

Cécile Lorrain, Ivona Glavincheska
1 citations
BMC Biology
Genomics and Chromatin Dynamics
0.81
article

Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen

Cécile Lorrain, Ivona Glavincheska
article en
1 citations

Abstract

Our study uncovers the multi-scale principles of nuclear organization in a major fungal plant pathogen and reveals how hierarchical nuclear architecture contributes to gene expression coordination and genome stability. These findings establish a conceptual framework for investigating 3D genome function and chromatin-mediated regulation in filamentous fungi and other eukaryotic microbes.

BMC BiologyVol. 23(1)
ETH Zurich (CH)
Eidgenössische Technische Hochschule Zürich
Openalex Percentile: Top 21%
Genomics and Chromatin Dynamics
0.81
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