Three-dimensional genome architecture connects chromatin structure and function in a major wheat pathogen
Our study uncovers the multi-scale principles of nuclear organization in a major fungal plant pathogen and reveals how hierarchical nuclear architecture contributes to gene expression coordination and genome stability. These findings establish a conceptual framework for investigating 3D genome function and chromatin-mediated regulation in filamentous fungi and other eukaryotic microbes.
Authors
- Cécile Lorrain (ORCID: https://orcid.org/0000-0001-9727-2616)
- Ivona Glavincheska
Institutions
- ETH Zurich (CH)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s12915-025-02461-y
- Citations
- 1
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Eidgenössische Technische Hochschule Zürich