Identification of angiogenesis-related hub genes in proliferative diabetic retinopathy via integrated transcriptomics and machine learning
This study identified angiogenesis-related hub genes in PDR using transcriptomics and machine learning, and demonstrated that LAMB1 promoted angiogenic activity in HRECs, offering a potential therapeutic target for PDR.
Authors
- Yunhong Zhang (ORCID: https://orcid.org/0000-0002-2899-5068)
- Jie Zhao (ORCID: https://orcid.org/0000-0002-7622-8904)
- Yan Wang (ORCID: https://orcid.org/0000-0002-4006-5859)
- Q. Richard Lu (ORCID: https://orcid.org/0000-0001-6846-9014)
Institutions
- Yangpu Hospital of Tongji University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s13098-025-02029-4
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00