Intracavernosal Botulinum Toxin Injection for Erectile Dysfunction: A Comprehensive Systematic Review
Based on this systematic review, intracavernosal onabotulinumtoxinA (BoNT-A) may be a beneficial therapeutic option for patients with refractory ED, offering potential improvements in sexual function while reducing the need for invasive therapies. Future large-scale, placebo-controlled studies are essential to confirm these benefits and standardize their clinical application.
Authors
- D. Sánchez Zalabardo (ORCID: https://orcid.org/0009-0003-1803-580X)
- Marcos Torres Roca
- Francisco Guillén‐Grima (ORCID: https://orcid.org/0000-0001-9749-8076)
- J.E. Robles (ORCID: https://orcid.org/0000-0001-5698-641X)
- Vanessa Talavera Cobo (ORCID: https://orcid.org/0009-0000-2425-9795)
- B. Miñana (ORCID: https://orcid.org/0000-0001-7745-5650)
- F.J. Ancizu Marckert
- Andres Calva Lopez (ORCID: https://orcid.org/0009-0006-2503-9368)
- Luis Labairu Huerta (ORCID: https://orcid.org/0000-0002-3882-4203)
- Carlos Alberto Ruiz (ORCID: https://orcid.org/0000-0001-6635-5478)
- Carmina Alejandra Muñoz Bastidas (ORCID: https://orcid.org/0009-0000-1175-5706)
- F.J. Diez-Caballero Alonso
- M. Tapia (ORCID: https://orcid.org/0000-0002-2561-213X)
Institutions
- Universidad Pública de Navarra (UPNA) (ES)
- Instituto de Salud Carlos III (ES)
- Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (ES)
- Navarre Institute of Health Research (ES)
- Clinica Universidad de Navarra (ES)
- Medical Research Network (US)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Life
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3390/life15121826
- Primary Topic
- Sexual function and dysfunction studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00