Acquired factor XIII deficiency is associated with mortality and is not linked to hypocalcemia

Acquired factor XIII deficiency is associated with high morbidity and mortality rates. In the setting of acquired FXIII deficiency, the level of FXIII required for haemostasis and endothelium stabilization seem to be around 40%. Activation of FXIII seems to be warranted in order to stop bleeding.

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Publication Details

Journal
Blood Coagulation & Fibrinolysis
Published
2025-11-27
DOI
https://doi.org/10.1097/mbc.0000000000001400
Primary Topic
Blood properties and coagulation
Type
article
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article

Acquired factor XIII deficiency is associated with mortality and is not linked to hypocalcemia

Miguel López Esteban, Patricia Piñeiro, Marta Moreno-Carbonell, Cristina Pascual et al.
Blood Coagulation & Fibrinolysis
Blood properties and coagulation
article

Acquired factor XIII deficiency is associated with mortality and is not linked to hypocalcemia

Miguel López Esteban, Patricia Piñeiro, Marta Moreno-Carbonell, Cristina Pascual, Patricia Duque, Alberto Calvo, Estrella Terradillos, Pilar Lancho, Alicia Ortiz-Lopez
article en

Abstract

Acquired factor XIII deficiency is associated with high morbidity and mortality rates. In the setting of acquired FXIII deficiency, the level of FXIII required for haemostasis and endothelium stabilization seem to be around 40%. Activation of FXIII seems to be warranted in order to stop bleeding.

Blood Coagulation & FibrinolysisVol. 37(1)
Universidad Complutense de Madrid (ES), Union Bank of Switzerland (CH), Hospital General Universitario Gregorio Marañón (ES)
Openalex Percentile: Top 45%
Blood properties and coagulation
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Acquired factor XIII deficiency is associated with mortality and is not linked to hypocalcemia — Miguel López Esteban, Patricia Piñeiro, et al. · Blood Coagulation & Fibrinolysis (2025) | TGRS Research Map | TGRS