Baseline PET/CT metabolic parameters in the double-expressor subtype of diffuse large B-cell lymphoma: development of a clinical–radiologic–pathologic predictive model
TMTV, IPI, and Ki-67 are robust independent predictors of DEL. The integrated clinical-imaging-pathological prediction model constructed from these three parameters synergistically combines multi-dimensional information, significantly enhancing early DEL identification capability and facilitating the implementation of risk-adapted therapeutic strategies.
Authors
- Guoxiu Lu (ORCID: https://orcid.org/0000-0001-5085-6163)
- Guoxu Zhang (ORCID: https://orcid.org/0009-0005-1156-165X)
- Jigang Wang (ORCID: https://orcid.org/0000-0002-0575-0105)
- Peng Qi (ORCID: https://orcid.org/0000-0002-5048-9604)
- Jingjing Liang (ORCID: https://orcid.org/0000-0002-6766-4747)
Institutions
- General Hospital of Shenyang Military Region (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-28
- DOI
- https://doi.org/10.3389/fonc.2025.1660516
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00