Mechanisms of traditional Chinese medicine compound Danxiong granules for the treatment of radiation dermatitis based on network pharmacology, molecular docking and experimental validation
Overall, our findings suggest that TDX105 may exert anti-inflammatory effects through the inhibition of NF-κB and MAPK signaling pathways, providing a potential therapeutic approach for radiation dermatitis.
Authors
- Cunyu Feng
- Ning Du (ORCID: https://orcid.org/0000-0003-3025-4629)
- Yuting Ma (ORCID: https://orcid.org/0000-0001-6267-1852)
- Shuainan Liu (ORCID: https://orcid.org/0000-0002-6740-1605)
- Kejia Xu (ORCID: https://orcid.org/0009-0001-1659-4363)
- Min Wu (ORCID: https://orcid.org/0000-0002-3956-0107)
- Shuang Yu (ORCID: https://orcid.org/0000-0001-6565-3019)
- Aiping Tian (ORCID: https://orcid.org/0000-0002-4146-8254)
- Hui Cao (ORCID: https://orcid.org/0000-0002-1919-4787)
- Yi Huan (ORCID: https://orcid.org/0000-0002-4444-3941)
- Xu Hu (ORCID: https://orcid.org/0009-0005-0233-253X)
- Xinqi Liu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s12906-025-05194-1
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00