Effects of paternal preconception exposure to conventional and biologic DMARDs on newborn outcomes
While paternal use of methotrexate did not associate with adverse birth outcome, exposure to other immunosuppressants or biologic drugs may link to possible adverse birth outcomes despite small event numbers. This result highlight the importance of further clarification of drug safety in this field and medication use before planning a pregnancy, even in male patients.
Authors
- I‐Chieh Chen (ORCID: https://orcid.org/0000-0002-8345-5304)
- Yu‐Hsuan Joni Shao (ORCID: https://orcid.org/0000-0002-0757-1901)
- Chung‐Mao Kao (ORCID: https://orcid.org/0000-0002-2863-4350)
- Tzu‐Tung Kuo (ORCID: https://orcid.org/0000-0002-3571-7760)
- Yiming Chen (ORCID: https://orcid.org/0009-0002-8339-9389)
- Wei-Hao Wang (ORCID: https://orcid.org/0000-0003-4193-9025)
- Yen–Ju Chen (ORCID: https://orcid.org/0000-0002-9450-9144)
Institutions
- Taipei Medical University Hospital (TW)
- Taichung Veterans General Hospital (TW)
- Changhua Christian Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1186/s13075-025-03641-5
- Citations
- 1
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 1.88