Not All That Hurts Is Malignant: A Painful Case of Focal Nodular Hyperplasia

Focal nodular hyperplasia (FNH) is a benign hepatic lesion most often detected incidentally during imaging studies. While typically asymptomatic, a small subset of patients may present with abdominal pain or discomfort. Clinically and radiologically, FNH can mimic malignant liver tumors, occasionally resulting in unnecessary invasive procedures. This case report describes a 45-year-old woman with symptomatic FNH who was placed on routine imaging surveillance and managed conservatively. This case underscores the importance of accurately distinguishing this benign condition from hepatic malignancies. It further highlights the diagnostic challenges associated with achieving a definitive diagnosis.

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Publication Details

Journal
Cureus
Published
2025-11-28
DOI
https://doi.org/10.7759/cureus.97990
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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Not All That Hurts Is Malignant: A Painful Case of Focal Nodular Hyperplasia

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article

Not All That Hurts Is Malignant: A Painful Case of Focal Nodular Hyperplasia

Rajiv M. Patel, Khadija Warfa, Soraiya Manji, Zamanali Khakhar, A. A. Yunis, Sayed Ali, Dayib Buthul
article en

Abstract

Focal nodular hyperplasia (FNH) is a benign hepatic lesion most often detected incidentally during imaging studies. While typically asymptomatic, a small subset of patients may present with abdominal pain or discomfort. Clinically and radiologically, FNH can mimic malignant liver tumors, occasionally resulting in unnecessary invasive procedures. This case report describes a 45-year-old woman with symptomatic FNH who was placed on routine imaging surveillance and managed conservatively. This case underscores the importance of accurately distinguishing this benign condition from hepatic malignancies. It further highlights the diagnostic challenges associated with achieving a definitive diagnosis.

CureusVol. 17(11)
University of Nairobi (KE), Aga Khan University Hospital Nairobi (KE), Aga Khan University Nairobi (KE)
Openalex Percentile: Top 51%
Hepatocellular Carcinoma Treatment and Prognosis
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