Postmenopausal bleeding and hematometra revealing uterine carcinosarcoma

• Uterine carcinosarcoma is rare, aggressive, and often misdiagnosed. • Early detection is crucial, especially in low-resource settings. Postmenopausal bleeding is a common presentation of gynecological malignancies, often associated with endometrial carcinoma. However, uterine carcinosarcoma is a rare and aggressive malignancy that can present similarly. This case report describes a 55-year-old woman with postmenopausal bleeding and hematometra, raising a high clinical suspicion of endometrial carcinoma, who was ultimately diagnosed with uterine carcinosarcoma on histopathologic examination. This case highlights the diagnostic challenges and the importance of histopathological evaluation in atypical presentations.

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Publication Details

Journal
Current Problems in Cancer Case Reports
Published
2025-11-28
DOI
https://doi.org/10.1016/j.cpccr.2025.100399
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Postmenopausal bleeding and hematometra revealing uterine carcinosarcoma

Reza Ferdousi, Mohammad Delwer Hossain Hawlader, Mohammad Ashraful Amin, Raffaele Manna et al.
Current Problems in Cancer Case Reports
Uterine Myomas and Treatments
article

Postmenopausal bleeding and hematometra revealing uterine carcinosarcoma

Reza Ferdousi, Mohammad Delwer Hossain Hawlader, Mohammad Ashraful Amin, Raffaele Manna, Sumyta Rahman, Sabrina Nahin, Nasim A. Khan
article en

Abstract

• Uterine carcinosarcoma is rare, aggressive, and often misdiagnosed. • Early detection is crucial, especially in low-resource settings. Postmenopausal bleeding is a common presentation of gynecological malignancies, often associated with endometrial carcinoma. However, uterine carcinosarcoma is a rare and aggressive malignancy that can present similarly. This case report describes a 55-year-old woman with postmenopausal bleeding and hematometra, raising a high clinical suspicion of endometrial carcinoma, who was ultimately diagnosed with uterine carcinosarcoma on histopathologic examination. This case highlights the diagnostic challenges and the importance of histopathological evaluation in atypical presentations.

Current Problems in Cancer Case ReportsVol. 20
North South University (BD), Bangladesh Institute of Development Studies (BD), National Institute of Cancer Research and Hospital (BD), Dhaka Medical College and Hospital (BD)
Openalex Percentile: Top 53%
Uterine Myomas and Treatments
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